美國PeproTech公司是全球最大的重組細胞因子和蛋白生產(chǎn)商之一，始終致力于為生命科學研究開發(fā)重組蛋白及相關產(chǎn)品，如今已成為能提供多種高質(zhì)量細胞因子和重組蛋白，相應的單克隆、多克隆和生物素標記抗體，以及ELISA試劑盒的世界領導者。PeproTech.的產(chǎn)品涵蓋免疫調(diào)節(jié)蛋白、白介素、集落刺激因子、生長因子、無動物成分的重組蛋白、化學趨化因子、干擾素、脂聯(lián)素、成纖維生長因子、轉化生長因子、腫瘤壞死因子、神經(jīng)營養(yǎng)素和防御素等諸多生命科學研究領域中重要的生物活性分子。PeproTech公司的產(chǎn)品種類、規(guī)格齊全，更新速度快，且價格適中，已廣為中國的科研工作者所使用。

為跟蹤當今科研發(fā)展、滿足日益增長的需求，PeproTech公司追求不斷創(chuàng)新和與時俱進。PeproTech公司2016年12月推出2種新產(chǎn)品，分別是：

1. 重組人IL-12(HEK293 derived)

產(chǎn)品描述：IL-12 is a potent regulator of cell-mediated immune responses and it induces IFN-γ production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue-type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells, and induces the development of IFN-γ-producing Th1 cells. PeproTech's Recombinant Human IL-12 p70, derived from HEK293 cells, is a heterodimeric glycoprotein consisting of disulfide-linked p35 and p40 subunits (503 total amino acid residues). The calculated molecular weight of Human IL-12 p70 is 57.2 kDa; however, due to glycosylation, it migrates at an apparent molecular weight of 65-70 kDa based on SDS-PAGE gel, under non-reducing conditions.

2. 重組人HPRG

產(chǎn)品描述：

Histidine-proline-rich glycoprotein (HPRG), a member of the Cystatin structural superfamily, is an abundantly secreted multi-domain glycoprotein. Although the physiological function is largely unknown, HPRG potentially regulates physiological processes such as cell adhesion and migration, fibrinolysis, coagulation, complement activation, immune complex clearance and phagocytosis of apoptotic cells. HPRG can exert anti-angiogneic activity by stimulating apoptosis of endothelial cells. Recombinant Human HPRG is a 57.7 kDa glycoprotein containing 507 amino acid residues.
 

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