近年來，外泌體的研究熱度持續攀升，已成為當前生命科學和基礎醫學研究的一大熱點。數據顯示，在 2023 年國家自然科學基金獲批項目中，外泌體研究相關項目的總數近 390 個，立項的總金額突破 1.5 億元。

       近日，Quantum Design中國順利將NanoView全自動外泌體熒光檢測分析系統安裝于重慶大學醫學院，并為用戶進行了詳細的儀器介紹和操作培訓。我們相信設備優異的外泌體表征性能和Quantum Design中國專業的技術團隊將助力重慶大學醫學院在外泌體領域的研究取得重要進展！

重慶大學醫學院

       全自動外泌體熒光檢測分析系統是一款無需純化、全自動的可對單個外泌體進行表征分析的全新設備。該設備能夠提供全面的外泌體表征信息，包括外泌體粒徑大小、計數、分布、攜帶蛋白表達、生物標志物（CD9，CD81，CD63等）共定位等。設備操作簡單，結果可靠，有效降低了實驗操作難度，提高了實驗效率。短短三年，在世界范圍內已有100多家實驗室采用該設備，包括了著名的哈佛大學、約翰霍普金斯大學、康奈爾大學、洛杉磯兒童醫院、麻省總醫院、東京工業大學、首爾大學、新加坡國立大學、大阪大學、北京大學、上海交通大學、西安交通大學、中國海洋大學、重慶大學等，發表SCI已超過280篇，其中不乏頂級期刊如Cell、Nature、Journal   of Extracellular Vesicles、Cancer Research、Nanoscale、ACS Nano、BMJ journal、Brain Behavior Immunity、Trends in Cancer等。

全自動外泌體熒光檢測分析系統安裝完成

Quantum Design中國工程師向客戶講解實驗原理

NanoView全自動外泌體熒光檢測分析系統測試數據

近三年Exoview高水平文章精選列表：

• Jingjing Zhang   Eduardo …& Reátegui. (2023) Engineering a tunable micropattern-array   assay to sort singleextracellular vesicles and particles to detect RNA and   protein in situ. Journal of Extracellular Vesicles.

• Benjamin Cappe   …& Franck B. Riquet. (2023) Systematic compositional analysis of exosomal   extracellular vesicles produced by cells undergoing apoptosis, necroptosis   and ferroptosis. Journal of Extracellular Vesicles.

• Kotb Abdelmohsen   …& Myriam Gorospe. (2023) urvey of organ-derived small extracellular   vesicles and particles (sEVPs) to identify selective protein markers in mouse   serum. Journal of Extracellular Vesicles.

• Sara Hassanpour   Tamrin …& Arindom Sen. (2023) Critical considerations in determining the surface charge of small extracellular vesicles. Journal of Extracellular Vesicles.

• Gijung Kwak   …& Jung Soo Suk. (2023) Extracellular vesicles enhance pulmonary   transduction of stably associated adeno-associated virus following   intratracheal administration. Journal of Extracellular Vesicles.

• Andras Saftics  …& Tijana Jovanovic-Talisma. (2023) Single Extracellular VEsicle Nanoscopy. Journal of Extracellular Vesicles.

• Richard J. R. Kelwick …& Paul S. Freemont. (2023) Opportunities to accelerate extracellular vesicle research with cell-free synthetic biology. Journal of Extracellular Vesicles.

• Laurence Blavier …& Yves A. DeClerck. (2023) The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche. Journal of Extracellular Vesicles.

• Hongyun Wang ……& Junjie Xiao. (2022) Extracellular vesicles enclosed-miR-421 suppresses air pollution (PM2.5)-induced cardiac dysfunction via ACE2 signalling. Journal of Extracellular Vesicles.

• Linglei Jiang……& Santosh Dhakal. (2022) A7 bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type and Delta variants. Journal of extracellular vesicles.

• Shaobo Ruan, Nina Erwin, Mei He. (2022) Light-induced high-efficient cellular production of immune functional extracellular vesicles. Journal of extracellular vesicles.

• Nasibeh Karimi ……&  Cecilia Lässer. (2022) Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma – Contributions of platelet extracellular vesicles in plasma samples. Journal of Extracellular Vesicles.

• Heikki Kyykallio ……& Pia R-M Siljander. (2022) A quick pipeline for the isolation of 3D cell culture-derived extracellular vesicles. Journal of Extracellular Vesicles.

• Roberto Frigerio ……& Marina Cretich. (2022) Comparing digital detection platforms in high sensitivity immune-phenotyping of extracellular vesicles. Journal of Extracellular Vesicles.

• Yael Hirschberg ……& Inge Mertens. (2022) Characterizing extracellular vesicles from individual low volume cerebrospinal fluid samples, isolated by SmartSEC. Journal of Extracellular Vesicles.

• Sukhbir Kaur……& David D. Roberts. (2022) Single vesicle analysis of CD47 association with integrins and tetraspanins on extracellular vesicles released by T lymphoblast and prostate carcinoma cells. Journal of Extracellular Vesicles.

• Simone M. Crivelli……& Erhard Bieberich. (2022) Function of ceramide transfer protein for biogenesis andsphingolipid composition of extracellular vesicles. Journal of Extracellular Vesicles.

• Gi Beom Kim …& In-San Kim. (2023) Harnessing Oncolytic Extracellular Vesicles for Tumor Cell-Preferential Cytoplasmic Delivery of Misfolded Proteins for Cancer Immunotherapy. Small.

• J. Klein, Y. Cao. (2023) Multi-Lipid Synergy In Cartilage Lubrication: Redundancy Or Evolution? Osteoarthritis and Cartilage.

• Valerie DeLuca …& Michael E. Berens. (2023) Extracellular vesicles as a pharmacodynamic reporter in glioblastoma. Cancer Research.

• Sarah Pike …& Liya Xu. (2023) Extracellular vesicles in diagnostic retinoblastoma aqueous humor correlate with disease stage and clinical outcome: a pilot study. Cancer Research.

• D. Cookson …& Y. Ashraf Kharaz. (2023) The Biological Response Of Anterior Cruciate Ligamentocytes Following Treatment With Synovial Fluid Extracellular Vesicles. Osteoarthritis and Cartilage.

• Mei Lu …& Yuanyu Huang. (2023) Antitumor synergism between PAK4 silencing and immunogenic phototherapy of engineered extracellular vesicles. Acta Pharmaceutica Sinica B.

• Luke C. McIlvenna ……& Martin Whitham. (2023) Single vesicle analysis reveals the release of tetraspanin positive extracellular vesicles into circulation with high intensity intermittent exercise. The Journal of Physiology.

• Joseph Blommer ……& Dimitrios Kapogiannis. (2023) Extracellular vesicle biomarkers for cognitive impairment in Parkinson’s disease. BRAIN.

• Tyler J ……& Atta Behfar. (2022) Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence. Npj Regenerative Medicine.

• Min Han ……& Tao Xin. (2022) Three-Dimensional-Cultured MSC-Derived Exosome-Hydrogel Hybrid Microneedle Array Patch for Spinal Cord Repair. Nano Letters.

• Zijian Yang ……& David A. Issadore. (2022) Ultrasensitive Single Extracellular Vesicle Detection Using High Throughput Droplet Digital Enzyme-Linked Immunosorbent Assay. Nano Letters.

服務推出至今，短短兩年時間已經助力多個中國客戶發表高水平文獻！

■ 南方醫科大學在《Chemical Engineering Journal》發表文章

■ 南方醫科大學珠江醫院在《Bioengineering & Translational Medicine》發表文章

■ 上海大學在《Journal of extracellular vesicles》發表文章

■ 中國科學院深圳先進技術研究院在《Lab on a Chip》發表文章

■ 北京天壇醫院、國家納米科學中心、北京航空航天大學在《Advanced Science》發表文章

■ 同濟大學附屬上海市肺科醫院、上海思路迪轉化醫學團隊在《Journal of Nanobiotechnology》發表文章

■ 山東千佛山醫院在《NANO LETTERS》發表文章

■ 陜西師范大學在《Food & Function》發表文章

■ 南京大學在《Frontiers in Cell and     Developmental Biology》發表文章

■ 中山大學在《ACS NANO》發表文章

■ 北京理工大學在《Acta Pharmaceutica   Sinica B》發表文章

■ 中南大學湘雅二醫院在《International Journal of Nanomedicine》發表文章

樣機體驗：

       為了更好的服務中國客戶，Quantum Design 中國子公司在北京建立了專業的客戶服務中心，正式推出專業的全面外泌體表征測試服務，您只需要極少量樣品即可獲得全面的外泌體表征數據！歡迎各位老師垂詢！

相關產品

1、全自動外泌體熒光檢測分析系統

2、ExoView外泌體全面表征試劑盒